Skip to main content
. 2020 Jul 15;11(10):2017–2023. doi: 10.1021/acsmedchemlett.0c00176

Table 4. Properties of Compound 7.

graphic file with name ml0c00176_0008.jpg

Compound UUIa IC50 (μM) MIAb IC50 (μM) Cmaxc (μg/mL) Exc.d (%) CYP2C9 IC50 (μM)
2g 8.8 24 1.36 0.35  
7 19.2 59 3.81 0.6 57
BBR 6.8 3.1 4.42 0 0.041
a

UUI and

b

MIA are defined in Table 1.

c

Cmax and

d

Exc. are defined in Table 3.