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. 2020 Jul 15;11(10):2017–2023. doi: 10.1021/acsmedchemlett.0c00176

Table 6. Urate Transporter 1 Inhibition and UUI of 1,2-Dihydro-3H-1,3-benzothiazole Derivatives and BBR.

Compound URAT1 inhibitiona (%) UUIb (%)
7 30 42
9 71 49
10 29 25
11 78 81
13 36 32
15 44 57
BBR 37 51
a

URAT1 inhibitory activity; % inhibition at 0.1 μM.

b

UUI are defined in Table 1, % inhibition at 10 μM.