Table 1. Kinase Inhibitory Activities of Compounds.

^aValues determined using an Omnia Kinase Assay at 250 μM ATP.

^bpFGFR4 and pFGFR2 formation in Huh7 and KATO cells, respectively.

^cInhibition of FGFR2 phosphorylation was used as a surrogate for FGFR1 and FGFR3, as potencies against these off-targets were similar.