Table 1. Inhibitory Activity of Compounds 1–8.
Compound | IC50 against E. coli MS 200–1 (μM) | In vitro IC50 against CutC (μM) |
---|---|---|
1 | 6,300 ± 1,800 | 840 ± 100 |
2 | 950 ± 340 | 2,000 ± 300 |
3 | 1,600 ± 300 | 7,000 ± 2,000 |
4 | 760 ± 150 | 2,600 ± 1,100 |
5 | 27,000 ± 4,000 | >10,000 |
6 | 10 ± 4 | 2.9 ± 0.7 |
7 | 920 ± 80 | 420 ± 100 |
8 | 1,800 ± 600 | N/Aa |
N/A = not available.