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. 2020 Mar 25;11(10):1980–1985. doi: 10.1021/acsmedchemlett.0c00005

Table 1. Inhibitory Activity of Compounds 18.

graphic file with name ml0c00005_0006.jpg

Compound IC50 against E. coli MS 200–1 (μM) In vitro IC50 against CutC (μM)
1 6,300 ± 1,800 840 ± 100
2 950 ± 340 2,000 ± 300
3 1,600 ± 300 7,000 ± 2,000
4 760 ± 150 2,600 ± 1,100
5 27,000 ± 4,000 >10,000
6 10 ± 4 2.9 ± 0.7
7 920 ± 80 420 ± 100
8 1,800 ± 600 N/Aa
a

N/A = not available.