TABLE 2.

Multivariable-adjusted linear regression of nutrition markers during pregnancy with rTL in placenta¹

Model	n	Placenta rTL, B (95% CI)	P
Prepregnancy BMI, kg/m2
1	89	−0.010 (−0.021, 0.0001)	0.053
2	88	−0.015 (−0.026, −0.005)	0.005
3	81	−0.022 (−0.035, −0.009)	0.001
Prepregnancy body weight, kg
1	89	−0.004 (−0.009, −0.0002)	0.042
2	89	−0.006 (−0.010, −0.001)	0.011
3	81	−0.007 (−0.012, −0.002)	0.005
Prepregnancy body fat percentage, %
1	89	−0.008 (−0.016, −0.001)	0.035
2	87	−0.012 (−0.019, −0.004)	0.004
3	81	−0.014 (−0.023, −0.006)	0.002
Height, cm
1	92	−0.001 (−0.009, 0.007)	0.762
2	91	−0.0001 (−0.008, 0.008)	0.985
3	83	0.0002 (−0.008, 0.007)	0.967
Hemoglobin third trimester, g/L
1	78	−0.005 (−0.009, −0.001)	0.014
2	75	−0.003 (−0.007, 0.001)	0.126
3	72	−0.002 (−0.006, 0.002)	0.275
Serum folate,2 nmol/L
1	85	0.001 (−0.007, 0.009)	0.733
2	82	0.005 (−0.003, 0.013)	0.211
3	81	0.003 (−0.004, 0.011)	0.368
Serum vitamin B-12,2 nmol/L
1	85	−0.304 (−0.761, 0.154)	0.190
2	82	−0.497 (−0.950, −0.044)	0.032
3	81	−0.473 (−0.918, −0.028)	0.038
Serum homocysteine,2 μmol/L
1	85	−0.004 (−0.039, 0.030)	0.802
2	82	−0.002 (−0.035, 0.032)	0.923
3	81	−0.010 (−0.043, 0.024)	0.566
Plasma 25(OH)D3,2 nmol/L
1	87	0.0024 (−0.0008, 0.0056)	0.135
2	84	0.0039 (0.0009, 0.0069)	0.012
3	81	0.0036 (0.0006, 0.0065)	0.019
Serum selenium,2 μg/L
1	88	0.0006 (−0.004, 0.002)	0.696
2	85	0.00002 (−0.003, 0.003)	0.991
3	81	0.0002 (−0.003, 0.003)	0.915
Serum magnesium,2 mg/L
1	88	−0.022 (−0.049, 0.006)	0.119
2	85	−0.006 (−0.034, 0.022)	0.673
3	81	0.004 (−0.024, 0.032)	0.769
Serum calcium,2 mg/L
1	88	−0.011 (−0.021, −0.002)	0.046
2	85	−0.003 (−0.014, 0.008)	0.565
3	81	−0.001 (−0.012, 0.010)	0.824
Blood zinc,2 mg/L
1	87	−0.019 (−0.073, 0.035)	0.484
2	84	−0.019 (−0.070, 0.031)	0.453
3	80	−0.014 (−0.065, 0.036)	0.570
Blood manganese,2 μg/L
1	87	0.001 (−0.005, 0.007)	0.709
2	84	0.004 (−0.002, 0.009)	0.212
3	80	0.003 (−0.003, 0.008)	0.333
Urine iodine,2 μg/L, log2-transformed
1	88	−0.004 (−0.047, 0.038)	0.846
2	85	−0.013 (−0.052, 0.026)	0.514
3	81	−0.012 (−0.052, 0.028)	0.550

¹Model 1 is unadjusted. Model 2 is adjusted for mother´s age, education, gestational week at delivery, and prepregnancy BMI (if not evaluated variable, or models for weight, height, or body fat mass). The model for plasma 25(OH)D₃ is additionally adjusted for season of sampling. Model 3 is further adjusted for other nutrients, i.e., vitamin B-12, plasma 25(OH)D₃, and season of sampling. rTL, relative telomere length; 25(OH)D₃, 25-hydroxycholecalciferol.

²During pregnancy (mean gestational week 27).