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. 2020 Aug 28;150(10):2716–2728. doi: 10.1093/jn/nxaa239

FIGURE 2.

FIGURE 2

Cecal and fecal baseline microbial composition in B6, DBA, and FVB mice and correlation with adiposity gain. (A, B) Taxa bar plots of baseline cecal (A) and fecal (B) microbiota of 3 mouse strains at the phylum level. (C–H) Baseline abundance profiles for specific fecal microbiota of 3 mouse strains at the genus level. CLR values were used for plotting the abundance of each microbiota. Box-and-whiskers plots from minimum to maximum showing abundance distribution of Lactobacillus (C), unknown genus of Clostridiales (D), unknown genus of Lachnospiraceae (E), unknown genus of S24–7 (F), Akkermansia (G), and Turicibacter (H). The center line in the box denotes the median value. One-factor ANOVA followed by Sidak's post hoc test was conducted to calculate significant differences between the 3 mouse strains. Labeled means without a common letter differ, P < 0.05. n = 7–8/group. (I–N) Correlation analysis plots between microbiota baseline proportion and adiposity gain at week 12 of fructose treatment. r = Biweight midcorrelation (bicor) coefficient, P = Benjamini-Hochberg–adjusted P values. n = 7–8/group. B6, C57BL/6J; CLR, centered log-ratio; DBA, DBA/2J; FVB, FVB/NJ.