Table V.
Multivariate analysis using Cox proportional hazards model.
| Variable | P-value | Hazard ratio (95% CI) |
|---|---|---|
| Age | 5.92x10-6a | 1.03 (1.02-1.05) |
| Sex | 0.94627 | 0.99 (0.68-1.43) |
| Extent of surgery | 0.00106a | 0.71 (0.57-0.87) |
| Leukopenia grade | 0.00205a | 0.77 (0.65-0.91) |
| TMZ completed | 0.00252a | 1.80 (1.23-2.64) |
aP<0.05. Patient age, sex, extent of surgery and leukop3enia grade were analyzed for association with overall survival, and P-values are shown for each individual variable. Likelihood ratio test P=4.41x10-9. Cox multivariate proportional hazards analysis was performed using statistical computing language and survival analysis libraries (R version 4.0.2; R Foundation; ‘survival’ library version 3.2-3; ‘survminer’ library version 0.4.8). TMZ, temozolomide.