Table 3.
Comparisons of mean kmf value (top) and PSR value (bottom) between several cohorts, all healthy control subjects vs. all MS patients (first column), age-matched healthy controls vs all MS patients (second column), age-matched healthy controls vs. MS patients with high disability (EDSS > 2) (third column), and MS patients with low disability (EDSS ≤ 2) vs MS patients with high disability (EDSS > 2) (fourth column). No significant reductions were found.
kmf | |||||||
HC (non-matched) vs. MS |
HC vs. MS |
HC vs. MS High Disability |
MS Low vs. High Disability |
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Reduction | p-value | Reduction | p-value | Reduction | p-value | Reduction | p-value |
−7.17% | 0.98 | −0.86% | 0.83 | −6.17% | 0.44 | −2.85% | 0.78 |
PSR | |||||||
HC (non-matched) vs. MS |
HC vs. MS |
HC vs. MS High Disability |
MS Low vs. High Disability |
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Reduction | p-value | Reduction | p-value | Reduction | p-value | Reduction | p-value |
0.53% | 0.95 | −0.35% | 0.95 | 3.05% | 0.60 | 1.84% | 0.80 |
Comparison Results: kmf and PSR in Total White Matter Region.