Table 4.

Correlations between mean k_mf values and EDSS, CRT, PASAT, and SDMT scores for cohort of all MS patients, patients with established disability (EDSS >0), and the combined cohort of all healthy controls and all MS patients. Correlations were highest for EDSS scores in the MS patients with disability.

Correlation Statistic	kmf Region	MS Patients All		MS Patients EDSS >0		Healthy Controls and MS Patients
Clinical Measure		ρ	p	ρ	p	ρ	P
EDSS	Total	−0.79	<0.0001	−0.92	0.0001
	Prefrontal	−0.49	0.04	−0.61	0.06
	Parietal	−0.78	0.0001	−0.82	0.004
	Motor	−0.54	0.02	−0.69	0.03
	Sensory	−0.65	0.003	−0.66	0.04
CRT	Total	−0.60	0.008	−0.62	0.06	−0.53	0.0007
	Prefrontal	−0.26	0.30	−0.10	0.78	−0.30	0.07
	Parietal	−0.56	0.02	0.55	0.10	−0.51	0.001
	Motor	−0.62	0.006	0.54	0.11	−0.39	0.02
	Sensory	−0.75	0.0003	−0.76	0.01	−0.53	0.0007
PASAT	Total	0.24	0.33	0.11	0.76	0.31	0.06
	Prefrontal	0.52	0.03	0.68	0.03	0.34	0.04
	Parietal	0.09	0.73	−0.21	0.56	0.23	0.18
	Motor	0.12	0.63	−0.26	0.46	0.15	0.39
	Sensory	0.12	0.65	−0.21	0.56	0.23	0.17
SDMT	Total	0.41	0.09	0.63	0.05	0.54	0.0006
	Prefrontal	0.38	0.12	0.45	0.19	0.44	0.007
	Parietal	0.31	0.22	0.46	0.18	0.44	0.006
	Motor	0.31	0.22	0.36	0.31	0.41	0.01
	Sensory	0.46	0.06	0.46	0.18	0.49	0.002

Correlation Results: cGM k_mf.