Table 2.
LGD mutation, antidepressant use by trimester, & maternal psychiatric history for LGD and antidepressant interaction group individuals
| Individual ID | 11453.p1 | 12521.p1 | 12645.p1 | 12673.p1 | 13069.p1 | 13647.p1 | 13711.p1 | 13809.p1 | 14667.p1 |
|---|---|---|---|---|---|---|---|---|---|
| Variant | sub(G->A) | del(4) | sub(C->T) | del(4) | sub(G->A) | del(1), del(2) | ins(T) | del(2) | sub(G->A) |
| Effect gene | PTPN13 | USP15 | ANK2 | TNRC6B | TCF7L2 | IL3, THAP5 | HECTD1 | CDC23 | RUNDC3B |
| Effect type | Splice-site | Frame-shift | Nonsense | Frame-shift | Splice-site | Both frame-shift | Frame-shift | Frame-shift | Nonsense |
| Antidepressants—trimester 1 use | Missing | No | No | Yes | Yes | Yes | Yes | Yes | Yes |
| Antidepressants—trimester 2 use | Missing | Yes | No | No | Missing | No | Yes | Yes | Yes |
| Antidepressants—trimester 3 use | Missing | Yes | Yes | No | Missing | No | Yes | Yes | Yes |
| Antidepressants—trimester not sure | Yes | No | No | No | Missing | No | No | No | No |
| Antidepressants during pregnancy | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Maternal depressive disorder | Yes | Yes | No | No | Missing | Yes | No | Yes | Yes |
| Maternal anxiety disorder | No | Yes | No | No | Missing | No | No | No | No |
| Maternal bipolar disorder | No | No | No | No | Missing | No | No | No | No |