Figure 1.
The schematic drawing of YAP, TAZ, and Yki. The key features of YAP, TAZ, and Yki are indicated (e.g., WW domain (WW) and TEAD-binding region (TB)). The major Hippo target sites where phosphorylation creates a binding site for 14–3-3 proteins are also highlighted (S127 of YAP, S89 of TAZ, and S168 of Yki).