Figure 3.

Bioinformatics target detection by different algorithms with respect to the presence of seed sequences. Downregulated transcripts at 12 h post-transfection of miR-17-5p (a), miR-517a-3p (b) and miR-135b-5p (c) were analysed. Black colour represents a fraction of targets possessing at least a single seed sequence and detected as true positives by a respective algorithm, white colour corresponds to not recognized mRNAs with seed sequences. Red colour shows transcripts without seed sequences but predicted as targets and blue colour – not recognized targets without seed sequence.