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Role of FTO in the regulation of lipogenic gene expression. (A) Primary hepatocytes stained with nile red, scale bar, 100 um. (B) TG content in CON, OA/DEX or OA/DEX+MA treated hepatocytes. (C-E) Protein content of SREBF1, SCD and GR in CON, OA/DEX or OA/DEX+MA treated hepatocytes. (F-G) Protein content of SREBF1 and SCD in CON, OA/DEX or OA/DEX+RU486 treated hepatocytes. Values are means ± SEM, *P < 0.05, **P < 0.01 (n = 3).
