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. 2018 May 28;11(5):334–345. doi: 10.1080/21541248.2018.1463895

Table 1.

RabGTPase alterations in cancer are frequently associated with the hallmarks of cancer invasion and metastasis.

Brain Lung Bladder  
Organs/RabGTPasesRab3 [101], Rab27 [102], Rab35 [32], Rab6 [103], Rab11 [104], Rab35 [78], Rab37 [105], (Rab11, Rab20, Rab23, Rab27) [106], Rab25 [107],  
Breast      
Rab2 [108], Rab4 [109], Rab5 [110112], Rab6 [113,114], Rab11 [115],      
Rab25 [116118], Rab27 [119121], Rab31 [122,123], Rab35 [32,39,74], Rab40 [124],
 
 
 
Esophagus
Colon/rectus
Stomach
Rab25 [125],
Rab1 [126], Rab3 [127], Rab5 [128], Rab25 [129],
Rab23 [130], Rab40 [131],
Liver
 
Pancreas
 
(Rab1, Rab4, Rab10, Rab22, Rab24, Rab25) [132], Rab5 [133], Rab23 [134], Rab27 [135],
 
Rab20 [136],
 
Cervix
Ovary
Prostate
Kidney
Rab5 [137], Rab35 [76],
Rab25 [116,138], Rab35 [72]
Rab7 [139], Rab25 [140]
Rab25 [141],
Skin
 
Blood
 
Rab7 [142], Rab11 [132], Rab35 [32],   Rab2 [143,144],  
 
 
Rab4 [145],
 
Tongue
Head, neck and oral squamous cell carcinoma
Mesothelioma
Rab1 [146] (Rab5, Rab7, Rab11) [147], Rab25 [148,149], Rab7 [138]

Superscripts refer to reference. The table shows reports of RabGTPase alterations in different organs and tissues, many of which were reported to be related with metastasis.