Table 2.
The classification of validated methods in publications and the score assignment according to ECO.
| Evidence levels | Evidence & Conclusion Ontology (ECO) | Experiment score (Ee) |
|---|---|---|
| Prediction | ECO:0007672: computational evidence | 0.05 |
| High-throughput expression | ECO:0000221: high throughput nucleotide sequencing assay evidence | 0.1 |
| ECO:0000093: array-based sequence capture evidence | 0.1 | |
| Low-throughput expression | ECO:0001554: methylation assay evidence | 0.2 |
| ECO:0001096: mass spectrometry evidence | 0.2 | |
| ECO:0005516: molecule detection assay evidence | 0.2 | |
| Function and mechanism | ECO:0001565: cell-based assay evidence | 0.4 |
| ECO:0000021: physical interaction evidence | 0.4 | |
| ECO:0000049: reporter gene assay evidence | 0.4 | |
| ECO:0000015: mutant phenotype evidence | 0.4 | |
| In vivo | ECO:0000178: in vivo assay evidence | 0.6 |
| Method unclear | ECO:0000352: evidence used in manual assertion | 0.2 |