LINC01198 activated PI3 K/AKT signalling pathway in glioma. (A, B) The protein levels of AKT, p-AKT (T308), mTOR and p-mTOR in glioma cells under indicated transfections were tested by Western blotting. (C) The effect of SC79 on shLINC01198#1 or shLINC01198#2-affected glioma cell proliferation and apoptosis was measured by MTT, EdU (scale bar = 100 μm), colony formation, TUNEL (scale bar = 100 μm) and Western blot assays in both U87 and U251 cells. **P < 0.01.