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Distribution of 3′-end processing sequence elements in human pre-mRNAs. The positions of AAUAAA (red), AUUAAA (yellow), single-nucleotide variants of AAUAAA or AUUAAA (green, labeled as AAUAAA–1), and UGUA (blue) motifs in the last 120 nts of known human mRNAs are shown, as a function of the distance to the cleavage site.
