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(A-C.) The midpiece (A., principle piece (B), and end piece (C) region of the sperm flagellum in cross section. The upper figures indicate the wild-type sperm, and figures at the bottom indicate the Tbc1d21 -/- sperm tails. Mitochondria (MS), outer dense fiber (ODF), and axoneme have been indicated. Red arrows and stars indicate the defective MS and axoneme structure, respectively, in the Tbc1d21 knockout sperm.
