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Simulation of the effect of Moxifloxacin at effective free therapeutic plasma concentration (10.96μM, see Table F in S1 Text) on the FP (from one electrode) and intracellular calcium transient (from one well) for two different heterogeneity fields. A finite element mesh of 96-well MEA device from Axion Biosystems was used for this simulation (see right panel of Fig 3).
