Table 3.
The Association Between Plasma Circ_0004771 Expression and the Clinicopathological Parameters in GC Patients
| Parameter | No. of Patients | Circ_0004771 (High) | Circ_0004771 (Low) | P-value |
|---|---|---|---|---|
| Age | ||||
| <60 | 43 | 24 | 19 | 0.341 |
| ≥60 | 77 | 36 | 41 | |
| Sex | ||||
| Male | 83 | 46 | 37 | 0.075 |
| Female | 37 | 14 | 23 | |
| Tumor size | ||||
| <5 | 106 | 51 | 55 | 0.255 |
| ≥5 | 14 | 9 | 5 | |
| Differentiation grade | ||||
| Well | 24 | 4 | 20 | <0.0001**** |
| Poor-moderate | 96 | 56 | 40 | |
| T stage | ||||
| T1–T2 | 77 | 28 | 49 | <0.0001**** |
| T3–T4 | 43 | 32 | 11 | |
| Lymph node metastasis | ||||
| Positive | 48 | 31 | 17 | 0.009** |
| Negative | 72 | 29 | 43 | |
| TNM stage | ||||
| I–II | 93 | 41 | 52 | 0.016* |
| III–IV | 27 | 19 | 8 | |
| Nerve/vascular invasion | ||||
| Positive | 40 | 21 | 19 | 0.699 |
| Negative | 80 | 39 | 41 | |
| CEA | ||||
| Positive | 60 | 35 | 25 | 0.068 |
| Negative | 60 | 25 | 35 | |
| CA199 | ||||
| Positive | 36 | 19 | 17 | 0.69 |
| Negative | 84 | 41 | 43 | |
| PGI | ||||
| Positive | 40 | 21 | 19 | 0.699 |
| Negative | 80 | 39 | 41 | |
| PGII | ||||
| Positive | 52 | 27 | 25 | 0.713 |
| Negative | 68 | 33 | 35 |
Notes: Asterisks (*) indicate statistical significance (*P<0.05, **P<0.01, ****P<0.0001).
Abbreviations: PG, pepsinogen; GC, gastric cancer.