Table 2. Fibrosis score and ultrasound variables of HBV patients measured at three points in time.
T1- 1st time point (At the baseline, on the last medication administered just before switching to TAF)
T2- 2nd time point (at the time of switch)
T3- 3rd time point (6± 0.5 months after switching to TAF)
* For the comparison between the first and the third point in time (McNemar testing using binomial distribution)
** For the comparison between the second and the third point in time (McNemar testing using binomial distribution)
a One patient was excluded from this point due to the missing data
HBV: hepatitis B virus
| T1 (n=71) | T2 (n=71) | T3 (n=70)a | P-value* | P-value** | |
| Fibrosis Score (n, %) | |||||
| F0 | 6(8.5%) | 3(4.2%) | 4(4.6%) | 0.001 | 0.485 |
| F1 | 13(18.3%) | 11(15.5%) | 8(11.3%) | ||
| F2 | 5(7.0%) | 5(7.0%) | 3(4.2%) | ||
| F3 | 6(8.5%) | 3(4.2%) | 3(4.2%) | ||
| F4 | 9(12.7%) | 6(8.5%) | 5(7.0%) | ||
| Ultrasound (n, %) | |||||
| Normal | 38(53.5%) | 32(45.1%) | 33(46.5%) | 0.001 | 0.406 |
| Fatty | 14(19.7%) | 13(18.3%) | 15(21.1%) | ||
| Cirrhotic | 11(15.5%) | 11(15.5%) | 11(15.5%) | ||