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. 2020 Sep 11;12(9):e10380. doi: 10.7759/cureus.10380

Table 2. Fibrosis score and ultrasound variables of HBV patients measured at three points in time.

T1- 1st time point (At the baseline, on the last medication administered just before switching to TAF)

T2- 2nd time point (at the time of switch)

T3- 3rd time point (6± 0.5 months after switching to TAF)

* For the comparison between the first and the third point in time (McNemar testing using binomial distribution)

** For the comparison between the second and the third point in time (McNemar testing using binomial distribution)

a One patient was excluded from this point due to the missing data

HBV: hepatitis B virus

  T1 (n=71) T2 (n=71) T3 (n=70)a P-value* P-value**
Fibrosis Score (n, %)
F0 6(8.5%) 3(4.2%) 4(4.6%) 0.001 0.485
F1 13(18.3%) 11(15.5%) 8(11.3%)
F2 5(7.0%) 5(7.0%) 3(4.2%)
F3 6(8.5%) 3(4.2%) 3(4.2%)
F4 9(12.7%) 6(8.5%) 5(7.0%)
Ultrasound (n, %)
Normal 38(53.5%) 32(45.1%) 33(46.5%) 0.001 0.406
Fatty 14(19.7%) 13(18.3%) 15(21.1%)
Cirrhotic 11(15.5%) 11(15.5%) 11(15.5%)