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. 2020 Jul 29;11(1):947–963. doi: 10.1080/21505594.2020.1793525

Figure 6.

Figure 6.

Attenuation of Sbi- and SpA-deficient S. aureus strains in the G. mellonella infection model. (a) Survival curves of G. mellonella larvae (n = 30) inoculated with 2.5 × 106 CFUs of S. aureus strain USA 300 or the isogenic sbi mutant strain. (b) Survival curves of G. mellonella larvae (n = 30) inoculated with 2.5 × 106 CFUs of S. aureus strain Newman or the isogenic spa mutant strain. Larval survival was assessed at 24, 48 and 72 h post infection. The statistical significance of the observed differences in the larval survival was assessed using a Wilcoxon test (Δsbi versus USA 300, P = 0.0484; Δspa versus Newman, P = 0.0068).