Table 2.
Multivariate Cox regression analysis for mortality (final model after variable selection using P < 0.10)
| Parameters | Stratified by region |
|||
|---|---|---|---|---|
| HR | 95% CI | P-value | ||
| Age (per 10 years) | 1.411 | 1.255 | 1.583 | <0.0001 |
| LVEF (per 5%) | 0.762 | 0.688 | 0.841 | <0.0001 |
| QTc (per 40 ms) | 1.322 | 1.173 | 1.431 | <0.0001 |
| COPD (yes vs. no) | 2.191 | 1.691 | 2.837 | <0.0001 |
| BMI (kg/m2) | 0.954 | 0.929 | 0.979 | 0.0004 |
| Haemoglobin (g/dL) | 0.887 | 0.827 | 0.951 | 0.0008 |
| Creatinine (mg/dL) | 1.224 | 1.080 | 1.386 | 0.0015 |
| NYHA (III vs. I–II) | 1.454 | 1.153 | 1.833 | 0.0016 |
| Sex (male vs. female) | 1.580 | 1.152 | 2.166 | 0.0045 |
| Diabetes (yes vs. no) | 1.265 | 0.999 | 1.600 | 0.0506 |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association.