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. 2020 Oct 13;161:105250. doi: 10.1016/j.phrs.2020.105250

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© 2020 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Meta-analysis of comorbidities in COVID-19 patients and typical related drugs. Cardiometabolic syndrome (cardiovascular disease, hypertension, and diabetes) was associated with worse clinical outcome of COVID-19 in affected patients. Drugs used for management or treatment of comorbidities: antihypertensives, antiarrhythmics, lipid lowering drugs (statins) listed could increase poor clinical outcome in comorbid patients by potential interaction with drugs used in the course of COVID-19. *indication for both pulmonary hypertension and erectile dysfunction.