Table 1.
Demographic and clinical characteristics of groups
| Characteristic | Pre-intervention group (n = 375) | Intervention group (n = 205) | P value |
|---|---|---|---|
| Age at surgery, mean (SD) | 54.2 (14.8) | 56.0 (15.5) | 0.17 |
| Sex, female n (%) | 199 (53.1) | 116 (56.6) | 0.42 |
| Diagnosis/type of surgery | 0.72 | ||
| Benign tumour, n (%) | 163 (43.5) | 86 (42.0) | |
| Malignant tumour, n (%) | 212 (56.5) | 119 (58.0) | |
| AB prophylaxis | |||
| Cloxacillin, n (%) | 326 (86.9) | 5 (2.4) | < 0.01 |
| Cefuroxim, n (%) | 17 (4.5) | 189 (92.2) | < 0.01 |
| Clindamycin, n (%) | 32 (8.5) | 11 (5.4) | 0.19 |
| Gentamicin intraoperatively, n (%) | 112 (29.9) | 33 (16.1) | < 0.01 |
| Operation time, median (IQR) | 201 (142–306) | 182 (122–269) | 0.05 |
| Body mass index, median (IQR) | 25 (23–28) | 26 (22–29) | 0.59 |
| S-Albumin, mean (SD) | 37 (4.5) | 36.5 (4.5) | 0.18 |
| Smoking, n (%) | 45 (12.0) | 24 (11.7) | 0.08 |
| Length of stay, mean days (SD) | 9.6 (6.6) | 9.3 (6.0) | 0.59 |
| Reoperation (index), n (%) | 52 (13.9) | 23 (11.2) | 0.36 |
| Charlson comorbidity index > 1, n (%) | 188 (50.1) | 124 (60.5) | 0.02 |
| ASA class > 2, n (%) | 343 (91.5) | 189 (93.2) | 0.47 |
| Preoperative steroids, n (%) | 357 (95.2) | 191 (93.2) | 0.25 |