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. 2020 May 7;162(11):2849–2856. doi: 10.1007/s00701-020-04309-6

Table 2.

Surgical site infections, infection depth, bacteria type and treatments by pre-intervention and intervention group

Variable Pre-intervention group (n = 375) Intervention group (n = 205) P value
SSI, intention to treat, n (%) 50 (13.3) 11 (5.4) < 0.01
SSI per protocol, n (%) 48 (14.5) 11 (5.3) < 0.01
Reoperation due to SSI n, (%) 31 (8.3) 6 (2.9) 0.02
Type of reoperation, n (%)
  Skin wound revision 4 (1.1) 2 (1.0) 0.99
  Bone flap removal 7 (1.9) 1 (0.5) 0.27
  Intradural operation 20 (5.3) 4 (2.0) 0.05
Depth of SSI, n (%)
  Superficial 20 (5.3) 4 (2.0) 0.05
  Deep 3 (0.8) 1 (0.5) 0.99
  Organ/space 27 (7.2) 6 (2.9) 0.04
Use of additional iv antibiotics, days/100 operations 160 74 0.07
Use of additional po antibiotics, days/100 operations 445 114 < 0.01
Total use of additional antibiotics (IV + PO), days/100 operations 605 188 0.03
Additional outpatient visits, visits/100 operations 33 10 < 0.01
Bacteria type, n (%)a
  Staphylococcus aureus 10 (2.7) 3 (1.5) 0.56
  Coagulase-negative staphylococci 3 (0.8) 2 (1.0) 0.99
  Proprionebacterium acnes 22 (5.9) 4 (2.0) 0.04
  Other species 8 (1.8) 2 (1.0) 0.51
  Negative culture 12 (3.2) 1 (0.5) 0.43

aA total of 6 patients had cultures with more than bacteria type identified