Table 2.
Variable | Pre-intervention group (n = 375) | Intervention group (n = 205) | P value |
---|---|---|---|
SSI, intention to treat, n (%) | 50 (13.3) | 11 (5.4) | < 0.01 |
SSI per protocol, n (%) | 48 (14.5) | 11 (5.3) | < 0.01 |
Reoperation due to SSI n, (%) | 31 (8.3) | 6 (2.9) | 0.02 |
Type of reoperation, n (%) | |||
Skin wound revision | 4 (1.1) | 2 (1.0) | 0.99 |
Bone flap removal | 7 (1.9) | 1 (0.5) | 0.27 |
Intradural operation | 20 (5.3) | 4 (2.0) | 0.05 |
Depth of SSI, n (%) | |||
Superficial | 20 (5.3) | 4 (2.0) | 0.05 |
Deep | 3 (0.8) | 1 (0.5) | 0.99 |
Organ/space | 27 (7.2) | 6 (2.9) | 0.04 |
Use of additional iv antibiotics, days/100 operations | 160 | 74 | 0.07 |
Use of additional po antibiotics, days/100 operations | 445 | 114 | < 0.01 |
Total use of additional antibiotics (IV + PO), days/100 operations | 605 | 188 | 0.03 |
Additional outpatient visits, visits/100 operations | 33 | 10 | < 0.01 |
Bacteria type, n (%)a | |||
Staphylococcus aureus | 10 (2.7) | 3 (1.5) | 0.56 |
Coagulase-negative staphylococci | 3 (0.8) | 2 (1.0) | 0.99 |
Proprionebacterium acnes | 22 (5.9) | 4 (2.0) | 0.04 |
Other species | 8 (1.8) | 2 (1.0) | 0.51 |
Negative culture | 12 (3.2) | 1 (0.5) | 0.43 |
aA total of 6 patients had cultures with more than bacteria type identified