Table 2.

Adjusted hazard ratios of prognostic factor for cardiovascular and renal events in overall, male, or female patients.

	Overall patients (n = 1162)		Male (n = 672)		Female (n = 490)
	HR (95%CI)	P-value	HR (95%CI)	P-value	HR (95%CI)	P-value
hsCRP reduction ≥ 40%	0.971 (0.597–1.578)	0.9041	1.464 (0.849–2.524)	0.1706	0.224 (0.053–0.948)	0.0421
Sex	1.675 (1.005–2.793)	0.0478
Age ≥ 68 years	1.513 (0.968–2.365)	0.0689	1.487 (0.877–2.522)	0.1409	1.773 (0.749–4.199)	0.1929
Diabetes mellitus	3.763 (2.139–6.621)	< 0.0001	2.892 (1.516–5.516)	0.0013	7.487 (2.139–26.20)	0.0016
Hyperlipidemia	0.904 (0.585–1.399)	0.6515	0.908 (0.540–1.525)	0.7142	0.868 (0.388–1.944)	0.7316
Smoking	0.922 (0.694–1.224)	0.5752	0.941 (0.698–1.268)	0.6896	0.571 (0.174–1.875)	0.3559
Previous CV disease	3.263 (1.988–5.355)	< 0.0001	3.147 (1.686–5.876)	0.0003	3.672 (1.627–8.289)	0.0017

hsCRP reduction ≥ 40% indicates 40% or greater reduction in hsCRP at 6 months after initiation of antihypertensive medication.

HR, hazard ratio, 95% CI 95% confidence interval, CV cardiovascular.