Table 1.
Patents’ laboratory/embryological data following the first embryo transfer
| Fresh day-3 blastomere Bx | FET day-3 blastomere Bx | P value | |
|---|---|---|---|
| Group A1 | Group B1 | ||
| No. of patients | 236 | 132 | |
| Total no. of cycles | 347 | 182 | |
| Mean age (years) | 32.6 ± 4.8 | 32.3 ± 4.5 | 0.425 |
| Indications for PGT-M | |||
| Single gene disorders | 301 | 171 | |
| Chromosomal abnormalities | 37 | 10 | |
| Sex selection | 9 | 1 | |
| Mean OPU | 9.9 ± 4.8 | 17.23 ± 8.9 | < 0.001 |
| Mean 2PN | 7.2 ± 3.9 | 10.7 ± 5.9 | < 0.001 |
| Mean FR | 0.74 ± 0.2 | 0.65 ± 0.2 | < 0.001 |
| Mean no of day-3 biopsied embryos | 5.6 ± 3.3 | 5.9 ± 2.9 | 0.368 |
| Total number of 2PN | 2509 | 1940 | |
| Total number of embryos cryopreserved | 1547 | ||
| Total number of embryos thawed | 1162 | ||
| Embryos survived post-thawing (%) | 1082/1162 (93.1) | ||
| Total number of embryos biopsied | 1964 | 1078 | |
| Total number of embryos with complete diagnosis | 1639 | 880 | |
| Embryos with complete diagnosis per embryo biopsied (%) | 1639/1964 (83.5) | 880/1078 (81.6) | 0.208 |
| No. of ETs | 253 | 152 | |
| No. of embryos transferred | 324 | 207 | |
| Ongoing PR (%) | 75/253 (29.6) | 40/152 (26.3) | 0.467 |
| Ongoing implantation rate (%) | 84/324 (25.9) | 46/207 (22.2) | 0.327 |
FET frozen-thawed embryo transfer