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. 2020 Sep 29;11:576903. doi: 10.3389/fimmu.2020.576903

Figure 2.

Figure 2

Silencing of hsa_circ_0060450 promotes IFN-I-induced inflammation through the JAK-STAT1/3 pathway. (A) RT-qPCR analyses of hsa_circ_0060450 to confirm the silencing efficiencies of two siRNAs. (B) RT-qPCR analyses of IFIT1, IFIH1, CXCL10, and iNOS under IFN-I stimulation after treatment with two hsa_circ_0060450 siRNAs. (C) STAT1 and STAT3 protein phosphorylation assessment at 15 and 30 min of IFN-I stimulation after treatment with two hsa_circ_0060450 siRNAs. NC, negative control. Data represent means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001.