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. 2020 Sep 29;11:568636. doi: 10.3389/fimmu.2020.568636

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Copyright © 2020 Garcia-Castillo, Tomokiyo, Raya Tonetti, Islam, Takahashi, Kitazawa and Villena.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Lacticaseibacillus rhamnosus CRL1505 on broncho-alveolar lavages (BAL) leucocytes variations and CXCL1 and IL-17 levels in response to Respiratory Syncytial Virus (RSV) infection. Infant mice were orally treated with L. rhamnosus CRL1505 or Lactiplantibacillus plantarum CRL1506 (10⁸ cell/mouse/day) during five consecutive days. One day after the last lactobacilli administration, mice were challenged with RSV. The numbers of BAL leucocytes, neutrophils, lymphocytes, and macrophages/monocytes were evaluated before (basal) and 2 days after the RSV infection. The levels of BAL CXCL1 and IL-17 were measured 2 days after RSV challenge. The results represent data from three independent experiments. Asterisks indicate significant differences when compared to the control group. *P < 0.05.