Table 1.
Demographic and stimulation characteristics of the 78 couples undergoing infertility treatments
| Parameter | Values |
|---|---|
| Age | |
| Female age (n = 78) (years) | 38.3 ± 4.3 (27–49) |
| Male age (n = 78) (years) | 39.3 ± 4.1 (29–48) |
| Karyotype | |
| Normal male karyotype rate (%) | 68/71 (95.8) |
| Abnormal male karyotype rate (%)a | 3/71 (4.2) |
| Normal female karyotype rate (%) | 69/72 (95.8) |
| Abnormal female karyotype rate (%)b | 3/72 (4.2) |
| Infertility | |
| Time of infertility (n = 77) (years) | 2.8 ± 2.1 (1–13) |
| Male factor only rate (%) | 31/78 (39.7) |
| Female factor only rate (%) | 32/78 (41.0) |
| Mixed factors-male + female-rate (%) | 6/78 (7.7) |
| Mixed factors-female + female-rate (%) | 9/78 (11.5) |
| Stimulation | |
| bFSH (n = 73) (mIU/mL) | 9.2 ± 4.9 (2.4–31.5) |
| AMH (n = 72) (ng/mL) | 2.4 ± 2.2 (0.1–13.5) |
| Follicle number (n = 77) | 9.5 ± 4.5 (1–20) |
| GnRH antagonist rate (%) | 75/78 (96.2) |
| GnRH agonist rate (%) | 3/78 (3.8) |
| Total GnRH dose (n = 78) (IU/mL) | 2647.1 ± 1239.2 (11–7250) |
| rFSH rate (%) | 31/78 (39.7) |
| rFSH + HMG rate (%) | 33/78 (42.3) |
| rFSH + rLH rate (%) | 12/78 (15.4) |
| HMG rate (%) | 2/78 (2.6) |
| Time of stimulation (n = 78) (days) | 9.0 ± 1.9 (1–13) |
| Estradiol (n = 74) (pg/mL) | 1596.8 ± 930.6 (229.3–4725.8) |
| Ovulation trigger | |
| rHCG rate (%) | 30/78 (38.5) |
| GnRH agonist rate (%) | 23/78 (29.5) |
| Dual trigger rate (rHCG + agonist) (%) | 25/78 (32.1) |
bFSH, baseline follicle-stimulating hormone; rFSH, recombinant FSH; AMH, anti-Müllerian hormone; GnRH, gonadotropin-releasing hormone; HMG, human menopausal gonadotropin; rLH, recombinant luteinizing hormone; rHCG, recombinant human choriogonadotropin
Values in n (rate); mean ± standard deviation (range)
aAbnormal male karyotypes 46Xinv(Y)(p11,2q11,22); 46XY,inv(3)(p26.1q13.1); 47XYY
bAbnormal female karyotypes 45X(3)/47XXX(2)/46XX(53); 46XX,t(10;12); 45X(3)46XX(55)