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. 2020 May 13;57(12):4649–4659. doi: 10.1007/s13197-020-04502-6

Table 1.

Central composite design factors levels

Coded levels Factors
X1 pH X2 liquid to solid material ratio X3 extraction time/h X4 extraction temperature/°C X5 double enzyme dose/U/g
 − 2 3.0 1:20 4 35 500
 − 1 3.3 1:25 5 40 700
0 3.6 1:30 6 45 900
1 3.9 1:35 7 50 1100
2 4.2 1:40 8 55 1300