Table 2.

Comparison of genotype and allele frequency of SRA1 gene rs801460, rs10463297, and rs250426 in PCOS patients and control group

	PCOS (n = 315)	Control (n = 315)	HWE p	OR (95%CI)*	p
rs801460
TT	131 (41.59%)	121 (38.41%)	0.17	1.00 (reference)
TC	125 (39.68%)	139 (44.13%)		0.83 (0.59–1.17)	0.34
CC	59 (18.73%)	55 (17.46%)		0.99 (0.64–1.54)	0.97
Dominance model				0.88 (0.64–1.21)	0.46
Recessive model				1.09 (0.73–1.64)	0.76
T	387 (61.43%)	381 (60.48%)		1.00 (reference)
C	243 (38.57%)	249 (39.52%)		0.96 (0.77–1.21)	0.77
rs10463297
CC	164 (52.06%)	115 (36.51%)	0.18	1.00 (reference)
CT	110 (34.92%)	141 (44.76%)		0.55 (0.39–0.77)	< 0.01
TT	41 (13.02%)	59 (18.73%)		0.49 (0.31–0.78)	< 0.01
Dominance model				0.53 (0.39–0.73)	< 0.01
Recessive model				0.65 (0.42–1.01)	0.06
C	438 (69.52%)	371 (58.89%)		1.00 (reference)
T	192 (30.48%)	259 (41.11%)		0.63 (0.50–0.79)	< 0.01
rs250426
TT	205 (65.08%)	223 (70.79%)	0.16	1.00 (reference)
TG	89 (28.25%)	80 (25.40%)		1.21 (0.85–1.73)	0.34
GG	21 (6.67%)	12 (3.81%)		1.90 (0.91–3.97)	0.12
Dominance model				1.30 (0.93–1.82)	0.15
Recessive model				1.80 (0.87–3.73)	0.15
T	499 (79.21%)	526 (83.49%)		1.00 (reference)
G	131 (20.79%)	104 (16.51%)		1.33 (0.99–1.77)	0.06

*Data were calculated by logistic regression analysis with adjusted for age, BMI, and age at menarche. PCOS polycystic ovary syndrome, HWE Hardy-Weinberg equilibrium, OR odds ratio, CI confidence interval