TABLE 1.

Database for circRNA research.

Name	URL	Function
circBase	http://www.circbase.org/	Collects the circular RNA information of many species, such as human, mouse, C. elegans, etc.
CircInteractome	https://circinteractome.nia.nih.gov/	Maps RBP- and miRNA-binding sites on human circRNAs; Designs primers and siRNA sequence of circRNAs.
CircNet	http://circnet.mbc.nctu.edu.tw/	Integrates the following information: identification of new circRNAs; genome annotation of circRNAs; the expression profile of circRNAs; the network of circRNA-miRNA -mRNA.
circRNABase	http://starbase.sysu.edu.cn/mirCircRNA.php	Integrates the published data to construct the interaction network of miRNA and circRNA, or circRNA and RBP.
circRNADb	http://reprod.njmu.edu.cn/circrnadb	Summarizes circRNAs that encode proteins; contains 32,914 human circRNAs.
Circ2Traits	http://gyanxet-beta.com/circdb/	Collects circRNAs potentially associated with human diseases or traits.
CIRCpedia	http://www.picb.ac.cn/rnomics/circpedia/	Provides annotations on circRNAs and variable shear events of different cell lines/tissues
Deepbase	http://deepbase.sysu.edu.cn/	Emphasizes the interaction of ceRNA molecular network; integrates the information related to circRNAs.
TSCD	http://gb.whu.edu.cn/TSCD/	Provides information of tissue-specific circRNAs in main tissues of human and mouse.
circRNA disease	http://cgga.org.cn:9091/circRNADisease/	Includes the data of the association between circRNAs and disease, the expression of circRNAs in the patients, the detection methods of circRNA
CSCD	http://gb.whu.edu.cn/CSCD	Collects cancer-specific circRNAs; elaborates the interaction between miRNA and circRNA, or circRNA and RBP; predicts variable splicing of related genes.

TSCD, tissue specific circRNA database; CSCD, cancer-specific circRNA database; RBP, RNA binding protein.