TABLE 3.

Circulating circRNAs as diagnostic biomarkers of CVD.

CVD type	CircRNAs	Source	Regulation	References
Myocardial infarction	MICRA	Peripheral blood	Up	Vausort et al. (2016)
	CircRNA_081881	Plasma	Down	Deng et al. (2016)
Congenital heart diseases	Hsa_circRNA_004183	Plasma	Down	Wu et al. (2019)
	Hsa_circRNA_079265	Plasma	Down	Wu et al. (2019)
	Hsa_circRNA_105039	Plasma	Down	Wu et al. (2019)
Hypertension	Hsa_circ_0037911	Whole blood	Up	Bao et al. (2018)
Cardiomyopathy	CircDNAJC6	Serum	Down	Sonnenschein et al. (2019)
	CircTMEM56	Serum	Down	Sonnenschein et al. (2019)
	CircMBOAT2	Serum	Down	Sonnenschein et al. (2019)
Heart failure	Hsa_circ_0062960	Plasma	Up	Sun et al. (2020)
Coronary artery disease	Hsa_circ_0124644	Peripheral blood	Up	Zhao et al. (2017)
	Hsa_circ_0001879	PBMCs	Up	Wang L. et al. (2019)
	Hsa_circ_0004104	PBMCs	Up	Wang S. et al. (2019)
	Hsa_circ_0001445	Plasma	Down	Vilades et al. (2020)
Atrial fibrillation	Hsa_circ_025016	Plasma	Up	Zhang J. et al. (2018)

PBMCs, peripheral blood mononuclear cells.