Table 1.
Genotypes | OPSCC n (%) |
Controls n (%) |
OR (95% CI) | p-value |
---|---|---|---|---|
ERP29 rs7114 | ||||
AA | 150 (60.0) | 177 (70.8) | Reference | |
AG | 84 (33.6) | 64 (25.6) | 1.69 (0.83–3.43) | 0.14 |
GG | 16 (6.4) | 9 (3.6) | 5.67 (1.27–25.26)* | 0.02 |
AA or AG | 234 (93.6) | 241 (96.4) | Reference | |
GG | 16 (6.4) | 9 (3.6) | 5.50 (1.19–25.38)** | 0.02 |
AA | 150 (60.0) | 177 (70.8) | Reference | |
AG or GG | 100 (40.0) | 73 (29.2) | 2.05 (1.04–4.05)*** | 0.03 |
A allele | 384 (76.8) | 418 (83.6) | Reference | |
G allele | 116 (23.2) | 82 (16.4) | 2.13 (1.20–3.78)**** | 0.02 |
OPSCC oropharynx squamous cell carcinoma, n number of patients or controls, OR odds ratio adjusted by age, smoking and drinking status, CI confidence interval.
The significant values are indicated by bold letters.
*Power of analysis (PA): 30.0%; **PA: 30.0%; ***PA: 72.0%; ****PA: 77.1%.