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. 2020 Oct 12;7:340. doi: 10.1038/s41597-020-00642-8

Table 2.

Replication rates between GTEx and publicly available eQTL from these analyses.

GTEx Brain Region # eQTL Replication (π1) of GTEx eQTL Replication (π1) of AMP-AD eQTL in GTEx
Meta-Analysis ROSMAP Mayo TCX Mayo CER Meta-Analysis ROSMAP Mayo TCX Mayo CER
Amygdala 158,270 0.974 0.987 0.986 0.916 0.356 0.421 0.701 0.555
Anterior Cingulate Cortex (BA24) 291,898 0.976 0.971 0.962 0.903 0.445 0.516 0.772 0.592
Caudate Basal Ganglia 435,939 0.966 0.961 0.935 0.881 0.488 0.544 0.781 0.636
Cerebellar Hemisphere 575,583 0.896 0.897 0.781 0.962 0.458 0.509 0.719 0.831
Cerebellum 819,435 0.893 0.890 0.711 0.936 0.526 0.577 0.761 0.863
Cortex 478,903 0.980 0.973 0.941 0.892 0.547 0.604 0.834 0.659
Frontal Cortex (BA9) 342,988 0.974 0.967 0.963 0.897 0.489 0.547 0.792 0.632
Hippocampus 221,876 0.967 0.970 0.937 0.905 0.404 0.462 0.710 0.570
Hypothalamus 227,808 0.974 0.966 0.960 0.913 0.392 0.436 0.719 0.580
Nucleus Accumbens Basal Ganglia 376,390 0.958 0.952 0.781 0.894 0.453 0.514 0.761 0.622
Putamen Basal Ganglia 293,880 0.966 0.974 0.930 0.890 0.433 0.493 0.764 0.591
Spinal Cord Cervical (c-1) 175,702 0.940 0.952 0.918 0.862 0.330 0.394 0.640 0.514
Substantia Nigra 120,582 0.964 0.951 0.960 0.928 0.297 0.372 0.635 0.479