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(A) The time-activity curves (TACs) of [18F]DPA714 accumulation in cortex and hippocampus of 12–13-months-old APP/PS1 (n = 8) and Wt (n = 8) mice using dynamic scan (60 min). (B) In blocking studies, the time-activity curves (TACs) of [18F]DPA714 accumulation in cortex and hippocampus pre-treated 12–13-months-old APP/PS1 mice (n = 8) with PK11195 10 min before radioligand administration.
