Table 1.
The impact of medicinal plants on the level of interleukin-17A (IL-17A) in neurodegenerative diseases.
| Authors | Disease | Medicinal plant | Effects on the level of IL-17A |
|---|---|---|---|
| Zhang Y. et al. (2015) | AD | Matrine | Reduction |
| Fragoulis et al. (2017) | AD | Kavalactones methysticin | Reduction |
| Chen et al. (2019) | AD | Oxymatrine | Reduction |
| Sanadgol et al. (2017) | MS | Ellagic acid | Reductiona |
| Zhang J. et al. (2015)/Wang et al. (2008) | MS | Tripchlorolide | Reductionb |
| Wang et al. (2012) | MS | Huperzine A | Reductionc |
| Zhao et al. (2011) | MS | Matrine | Reduction |
| Singh et al. (2007) | MS | Resveratrol | Reduction |
AD, Alzheimer’s disease; MS, Multiple sclerosis; aEllagic acid decreases IL-17A is dose-dependent; bTripchlorolide suppressed the mRNA levels of IL-17A; cHuperzine A down-regulates mRNA and protein levels of IL-17A.