Table 2.
Results of nerve conduction studies.
| SCA3(1) | PreSCA3(2) | Control (3) | p-value | Overall | |||
|---|---|---|---|---|---|---|---|
| 1 vs. 3 | 2 vs. 3 | 1 vs. 2 | P-value | ||||
| DML (ms) | |||||||
| Median nerve | 3.23 ± 0.50 | 2.81 ± 0.25 | 2.98 ± 0.34 | 0.032 | 0.216 | 0.001 | 0.002 |
| Ulnar nerve | 2.38 ± 0.44 | 2.14 ± 0.25 | 2.29 ± 0.30 | 0.375 | 0.188 | 0.08 | 0.072 |
| Tibial nerve | 3.61 ± 0.66 | 3.26 ± 0.61 | 3.59 ± 0.64 | 0.860 | 0.064 | 0.06 | 0.114 |
| Peroneal nerve | 3.71 ± 0.76 | 3.48 ± 0.51 | 3.20 ± 0.48 | 0.004 | 0.177 | 0.349 | 0.017 |
| CMAP amplitude (mV) | |||||||
| Median nerve | 13.59 ± 3.12 | 16.72 ± 3.68 | 15.34 ± 2.96 | 0.120 | 0.211 | 0.013 | 0.031 |
| Ulnar nerve | 13.83 ± 3.16 | 13.69 ± 2.85 | 15.20 ± 2.85 | 0.617 | 0.260 | 0.406 | 0.527 |
| Tibial nerve | 20.08 ± 8.55 | 21.42 ± 7.25 | 22.02 ± 8.21 | 0.126 | 0.115 | 0.570 | 0.175 |
| Peroneal nerve | 6.18 ± 2.89 | 9.00 ± 3.86 | 8.82 ± 3.17 | 0.003 | 0.832 | 0.059 | 0.007 |
SCA3, spinocerebellar ataxia type 3; PreSCA3, preclinical carriers of the SCA3 gene mutation; DML, distal motor latency; CMAP, compound muscle action potential; NA, not applicable. Values are mean ± SD. Values with significant differences printed in bold characters.