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. 2020 Oct 13;890:173643. doi: 10.1016/j.ejphar.2020.173643

Table 3.

Clinical Studies for evaluation of Lopinavir/Ritonavir and Interferons (https://clinicaltrials.gov/ct2/results).

Clinical Trial Number Study Description Phase Dose Location
NCT04276688 Utilization of Lopinavir/Ritonavir, Ribavirin and IFN-beta Combination against nCoV Treatment 2 Lopinavir/ritonavir:
400 mg and 100 mg respectively administered twice daily for 14 days
Ribavirin:
400 mg twice administered daily for 14 days
Interferon Beta-1B:
0.25 mg subcutaneous injection administered alternatively for 3 days
Hong Kong
NCT04251871 Treatment and Prevention of COVID-19 infection with Traditional Chinese Medicines Not Applicable alfa interferon: aerosol inhalation
lopinavir and ritonavir:400 mg of lopinavir and 100 mg of ritonavir bid for 2 weeks.
China
NCT04315948 Clinical Trial of various Treatments for Hospitalized adult patients against COVID-19 3 Lopinavir/ritonavir: 200 mg Lopinavir and 50 mg Ritonavir
IFN-ß-1a: one dose 44 μg/0.5 ml
France