Table 1.
EAE | N | EAE + WAS | N | P-value | |
---|---|---|---|---|---|
Mean day of onset | 11.50 ± 0.15 | 30/35 | 11.57 ± 0.21 | 30/35 | 0.7510 |
Peak score | 2.52 ± 0.19 | 2.52 ± 0.19 | 0.7036 | ||
Mean duration of remission | 38.00 ± 4.91 | 23.67 ± 3.66 | 0.0273* | ||
Mean day of first relapse onset | 55.33 ± 4.92 | 9/26 | 40.53 ± 3.43 | 15/28 | 0.0189* |
Peak score | 1.72 ± 0.41 | 2.20 ± 1.40 | 0.4066 | ||
Mean day of second relapse onset | 62.80 ± 6.00 | 5/26 | 52.40 ± 4.36 | 10/28 | 0.1885 |
Peak score | 3.00 ± 0.55 | 2.05 ± 0.28 | 0.1092 | ||
Mean day of third relapse onset | 66.00 ± 0 | 1/26 | 63.50 ± 2.92 | 6/28 | N.D. |
Peak score | 4 ± 0 | 2.42 ± 0.42 | N.D. | ||
Peak score (all relapse) | 2.50 ± 0.47 | 9/26 | 2.77 ± 0.29 | 15/28 | 0.6130 |
N corresponds to the number of animals with first surge or relapse divided by the total number of animals within the group (see Supplementary Figure 1A for a detailed description). The data are given for the animals that develop a first peak. P values are given for t-test or, when normality could not be assumed, Mann-Whitney’s U-test. *p < 0.05.