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Effect of Res on the expression of apoptotic proteins in H446 cells are assessed by western blotting. (A-D) Res at 40 µg/ml decreased the expression of (B) Bcl-2 and (D) Bcl-xL while it increased (C) Bax expression compared with that of the control (*P<0.05). By contrast, pretreatment of NAC at 2 mmol/l alleviated the effects of Res on the expression of Bcl-2, Bax and Bcl-xL, respectively (#P<0.05 vs. the Res group). Res, resveratrol; NAC, N-acetyl-L-cysteine.
