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. 2020 Sep 10;12(9):2766. doi: 10.3390/nu12092766

Figure 8.

Figure 8

The impact of Aronia melanocarpa L. berry extract (AE) on the ratios of matrix metalloproteinase-1 (MMP-1)/tissue metalloproteinase inhibitor-1 (TIMP-1), matrix metalloproteinase-2 (MMP-2)/tissue metalloproteinase inhibitor-2 (TIMP-2), and MMP-2/TIMP-1 in the livers of rats exposed to cadmium (Cd). The animals were treated with Cd at the concentrations of 0, 1, and 5 mg Cd/kg in their diets and/or 0.1% aqueous AE (+) or not (−). Data are shown as mean ± SE for eight rats, except for seven animals in the AE, Cd1, and Cd5 groups after 24 months. Statistically significant differences (Kruskal–Wallis post hoc test): * p < 0.05, ** p < 0.01, α p < 0.06, and β p < 0.08 vs. control group; † p < 0.05 vs. appropriate Cd group; ‡ p < 0.05 vs. AE group; # p < 0.05 vs. appropriate group maintained on the 1 mg Cd/kg diet (Cd1 group or Cd1 + AE group). Numerical values in bars express the percentage changes or factors of changes in comparison to the control group (↑, increase; ↓, decrease) or the appropriate group exposed to Cd alone (↙, decrease).