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. 2020 Sep 2;12(9):2679. doi: 10.3390/nu12092679

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Post-ischemic outcomes in untreated (−IPC) and preconditioned (+IPC) hearts from T2D mice ± dietary ALA supplementation. Hearts were subjected to 25 min ischemia/45 min reperfusion with or without prior IPC (3 × 5 min ischemia/reperfusion). Data are shown for (A) final left ventricular developed pressure (LVDP), and LVDP area under the curve throughout reperfusion; (B) final end diastolic pressure (EDP); (C) total post-ischemic efflux of LDH; and (D) post-ischemic nucleosome content. Results presented as means ± SEM (T2D (−IPC), n = 8; T2D (+IPC), n = 7; T2D + ALA (−IPC), n = 8; T2D + ALA (+IPC), n = 8). *, p < 0.05; and **, p < 0.01.