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. 2020 Aug 29;12(9):556. doi: 10.3390/toxins12090556

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Genomic islands identified in KE21 isolate. This Figure depicts two genomic islands (GIs) through the H. pylori KE21, with substantially lower GC content (average ~ 35.6%) compared to the remaining genome (average ~ 39.1%). (a) The Transposon Plasticity Zone (TnPZ), delimited by genes of putative FtsZ and 5S-23S rRNAs, and encoding a cluster of vir homolog genes for an integrated conjugative element of H. pylori type 4 secretion system of type 4 (ICEHptfs4). (b) The dg-region, delimited by genes encoding the 4-hydroxy-tetrahydrodipicolinate reductase (dapB) and the glutamate racemase (glr) and described, and encoding a cag pathogenicity island (cagPAI) region.