Table 14.
Changes in the antioxidant defense systems in NFD or HFD supplied mice.
| Items Groups | Glutathione (μM/mg Tissue) | Catalase (U/mg Tissue) | SOD (U/mg Tissue) |
|---|---|---|---|
| Controls | |||
| Intact | 65.20 ± 13.43 | 66.10 ± 20.85 | 8.88 ± 1.79 |
| HFD | 8.83 ± 2.12 a | 10.60 ± 4.14 a | 0.83 ± 0.56 a |
| Reference | |||
| Metformin | 31.32 ± 6.93 ac | 33.88 ± 10.15 ac | 3.50 ± 0.87 ac |
| Test materials—WL | |||
| 200 mg/kg | 56.87 ± 10.79 c | 51.89 ± 10.09 c | 6.48 ± 1.37 ac |
| 100 mg/kg | 48.10 ± 13.94 bc | 44.00 ± 15.61 bc | 4.94 ± 1.39 ac |
| 50 mg/kg | 34.03 ± 10.04 ac | 34.46 ± 13.53 ac | 3.59 ± 1.05 ac |
Values are shown as mean ± SD of eight mice. NFD = Normal pellet diet; HFD = 45% Kcal high-fat diet; WL = Wasabi Leaf/Folium, Wasabia japonica (Miq.) Matsum extracts; SOD = Superoxide dismutase. a p < 0.01 and b p < 0.05—vs. intact control; c p < 0.01—vs. HFD control.