Table 6.

Interruption of DOAC therapy before oral surgery.

Renal Function (CLCR mL/min)	Dabigatran		Rivaroxaban–Apixaban–Edoxaban
	Low-Risk Surgery	High-Risk Surgery	Low-Risk Surgery	High-Risk Surgery
≥80	24 h	48 h	24 h	48 h
50–79	36 h	72 h	24 h	48 h
30–49	48 h	96 h	24 h	48 h
15–29	Not indicated	Not indicated	36 h	48 h
<15	No official indication for use

Adapted from [28,56].