Table 7.

Frequency and severity of bleeding in previously published clinical trials.

Study	N of Procedures	Bleeding (%)	Degree	Dabigatran	Rivaroxaban	Apixaban	Edoxaban
Miranda et al. 2016 [3]	12	0		N.A.	N.A.	N.A.	N.A.
Clemm et al. 2016 [35]	16	0		0/6	0/8	0/2
Hanken et al. 2016 [20]	52	11.5	Two local compressions, four reoperations		6/52
Mauprivez et al. 2016 [29]	32	17.8	85.7% local compression, 14.3% reoperation	2/9	1/21	2/2
Morimoto et al. 2016 [38]	19	31.6	five local compression, one reoperation	0/4	3/9	3/6
Yagyuu et al. 2017 [37]	41	9.7	Minor bleeding	N.A.	N.A.	N.A.	N.A.
Lababidi et al. 2018 [6]	38	10.5	Minor bleeding	N.A.	N.A.	N.A.	N.A.
Yoshikawa et al. 2019 [31]	128	3.1	50% local compression, 50% reoperation	1/37	0/34	2/39	1/18
Berton et al. 2019 [36]	65	18.5	Local compression	1/11	3/28	1/22	0/4