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. 2020 Sep 16;44(5):1875–1884. doi: 10.3892/or.2020.7770

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — SERPINE1 suppression induces apoptosis in PTX-resistant TNBC cells. (A) Levels of cleaved caspase-3 and Bax proteins in the control and SERPINE1-knockdown MDA-MB-231 PTX-resistant cells. (B) Levels of cleaved caspase-3 and Bax proteins in the control and SERPINE1-knockdown MCF-7 PTX-resistant cells. (C) Quantification of cleaved caspase-3 protein levels in the control and SERPINE1-knockdown PTX-resistant cells. **P<0.01. (D) Quantification of Bax protein levels in the control and SERPINE-knockdown PTX-resistant cells. **P<0.01. SERPINE1, serine protease inhibitor, clade E member 1; PTX, paclitaxel; TNBC, triple-negative breast cancer.